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H4166 Sigma

Hydroxyflutamide

≥98% (HPLC)

Synonym: 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamide, 2-Hydroxyflutamide, Hydroxyniphtholide, Sch 16423, a,a,a-Trifluoro-2-methyl-4′-nitro-m-lactotoluidide

  • CAS Number 52806-53-8

  • Empirical Formula (Hill Notation) C11H11F3N2O4

  • Molecular Weight 292.21

  •  MDL number MFCD00563126

Properties

Related Categories Androgen, Approved Therapeutics/Drug Candidates, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones,
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   white to tan
solubility   DMSO: >10 mg/mL
storage temp.   room temp

Description

Biochem/physiol Actions

Hydroxflutamide is an AR antagonist. Androgen receptors (ARs) are nuclear hormone receptors/transcription factors. Hydroxyflutamide is an androgen antagonist with publications going back to 1981. It is one of a few gold standard AR antagonists; activities of new antagonists are measured against hydroxyflutamide.

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