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H7283 Sigma

Heat Shock Protein 70 human

recombinant, expressed in E. coli, buffered aqueous solution, ≥90% (SDS-PAGE)

Synonym: HSP 70

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Description

Physical form

Solution in 2.7 mM KCl, 1.5 mM KH2PO4, 137 mM NaCl, and 8.1 mM Na2HPO4.

Application

Heat shock protein 70 human has been used as a control for checking antibody reactivity.

Biochem/physiol Actions

HSPA8 (heat shock 70kDa protein 8) is a human cytoplasmic chaperone which is involved in protein folding, protein aggregation prevention and protein transport. During nutrient stress, it participates in antigen transport to regulate MHC (major histocompatibility) class II presentation. It is upregulated in cancer cells and is involved in protein homeostasis, leading to cancer cell growth and survival.

Price and Availability


All labs need water

Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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