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H7629 Sigma

γ-Butyrolactone

≥99% (GC)

Synonym: γ-Hydroxybutyric acid lactone, 4-Hydroxybutyric acid lactone, GBL

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Properties

Related Categories Building Blocks, Carbonyl Compounds, Cell Biology, Cell Signaling and Neuroscience, Chemical Synthesis,
vapor density   3 (vs air)
vapor pressure   1.5 mmHg ( 20 °C)
InChI Key   YEJRWHAVMIAJKC-UHFFFAOYSA-N
assay   ≥99% (GC)
autoignition temp.   851 °F
expl. lim.   16 %
refractive index   n20/D 1.436(lit.)
bp   204-205 °C(lit.)
mp   −45 °C(lit.)
density   1.12 g/mL at 25 °C(lit.)
storage temp.   2-8°C

Description

Biochem/physiol Actions

Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
LU3500000
Flash Point(F) 
208.4 °F
Flash Point(C) 
98 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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