• USA Home
  • H8502 - Dopamine hydrochloride

EMAIL THIS PAGE TO A FRIEND
H8502 Sigma

Dopamine hydrochloride

Synonym: 2-(3,4-Dihydroxyphenyl)ethylamine hydrochloride, 3,4-Dihydroxyphenethylamine hydrochloride, 3-Hydroxytyramine hydrochloride, 4-(2-Aminoethyl)-1,2-benzenediol hydrochloride

  • CAS Number 62-31-7

  • Linear Formula (HO)2C6H3CH2CH2NH2·HCl

  • Molecular Weight 189.64

  •  Beilstein Registry Number 3656720

  •  MDL number MFCD00012898

  •  PubChem Substance ID 24277897

  • Popular Documents:  FTNMR (PDF)  

Purchase

Description

Caution

Light sensitive

Packaging

5, 10, 25, 100 g in poly bottle

Application

• Dopamine hydrochloride has been used to study dopamine-mediated transient modulation of the physiological responses in whiteleg shrimp, Litopenaeus vannamei.
• It has been used to study dopamine-mediated changes in immunity susceptibility to Lactococcus garvieae in the freshwater giant prawn, Macrobrachium rosenbergii.
• It has been used to study the molecular link between dopamine-induced oxidative stress and mHtt (mutant Huntingtin) toxicity in relation to the activation of the autophagy pathway in an ‘in vitro’ model of parkinsonian Huntington′s Disease.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

General description

Dopamine (DA) works as neurotransmitter in the central nervous system. It is a catecholamine made from the amino acid L-tyrosine. It also works as a hormone in vesicles of the adrenal medulla, thereby controlling heart beat rate and blood pressure. Absence of DA-containing neurons is associated with parkinson’s disease.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H8502.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Price and Availability


Better Together

Discover your Target

Making Headway
Safety & Documentation

Safety Information

Symbol 
GHS09  GHS09
Hazard statements 
Personal Protective Equipment 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
Protocols & Articles

Articles

Discover Bioactive Small Molecules for Neuroscience

The nervous system, comprised of the brain and spinal cord (central nervous system, or CNS) and network of nerves that connects the CNS to the rest of the body (peripheral nervous system, or PNS) is ...
Keywords: Bioactive small molecules, Central Nervous System, Diseases, Metabolism, Neurodegenerative Diseases, Neuroscience, Neurotransmission, Neurotransmitters

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Stationary Phase Selectivity in Aqueous Normal-Phase/Hydrophilic Interaction Chromatographic (ANP/HILIC) Separations

The term aqueous normal-phase/hydrophilic interaction chromatography (ANP/HILIC) refers to liquid chromatography performed using highly organic (> 70%) mobile phases and relatively polar stationary p...
Carmen T. Santasania and David S. Bell
Reporter US Volume 24.5
Keywords: Applications, Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Methods, Neurotransmitters, Normal-phase chromatography, Reversed-phase chromatography, Separation

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

95199 Fluorescent Dopamine Neurotransmitter Ligand, labeled with Dansyl, suitable for fluorescence, ≥98% (HPLC)

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?