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Human Genetic Disease Analysis: A Practical Approach, 2nd ed.

  •  ISBN-10 0-19-963308-8

  •  ISBN-13 978-0-19-963308-1

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publication info   K.E. Davies, IRL Press at Oxford University Press, UK, 1993, 124 pp., soft cover
mfr. no.   Oxford University Press

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General description

This new edition covers all the important methods now commonly in use, including synthetic oligonucleotide hybridization, pulsed-field gel electrophoresis, and fluorescence in situ hybridization. This book describes not only the analysis of gene mutations but also the functional organization of genes and chromosome regions.

Table of Contents

1. Fetal DNA Analysis, J.M. Old
2. The Use of Synthetic Oligonucleotides as Specific Hybridization Probes in the Diagnosis of Genetic Disorders, S.W. Thein, A. Ehsani, and R.B. Wallace
3. Pulsed-field Gel Electrophoresis in the Analysis of Genomic DNA and YAC Clones, J.T. den Dunnen, P.M. Grootscholten, and G.J.B. van Ommen
4. Fluorescent in situ Hybridization, V.J. Buckle and K.A. Rack
5. Fine Mapping of Genes: The Characterization of the Transcriptional Unit, M. Antoniou, E. deBoer, and F. Grosveld
6. Chromosome Analysis and Sorting by Flow Cytometry, S. Monard, L. Kearney, and B.D. Young

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