|Related Categories||Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Detection and Quantitation, Multi-Drug Resistance,|
|color||white to tan|
|solubility||DMSO: >10 mg/mL|
Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters. Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. Steviol is a useful tool for studying renal drug clearance.
Simultaneous analysis of steviol and steviol glycosides by liquid chromatography with ultraviolet detection on a mixed-mode column: application to Stevia plant material and Stevia-containing dietary supplements. Jaworska K, Krynitsky AJ, and Rader JI J. AOAC Int. 95(6), 1588-96, (2012)
Simultaneous determination of steviol and steviol glycosides by liquid chromatography-mass spectrometry. Shah R, De Jager LS, and Begley TH Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 29(12), 1861-71, (2012)
Preparative separation and purification of rebaudioside a from steviol glycosides using mixed-mode macroporous adsorption resins. Liu Y, Di D, Bai Q, et al. J. Agric. Food Chem. 59(17), 9629-36, (2011)
Identification and quantification of major steviol glycosides in Stevia rebaudiana purified extracts by 1H NMR spectroscopy. Pieri V, Belancic A, Morales S, et al. J. Agric. Food Chem. 59(9), 4378-84, (2011)
Gas-phase intramolecular elimination reaction studies of steviol glycosides in positive electrospray and tandem mass spectrometry. Upreti M, Clos JF, Somayajula KV, et al. Eur. J. Mass Spectrom. (Chichester, Eng.) 15(1), 11-21, (2009)
Synthesis and antituberculosis activity of novel unfolded and macrocyclic derivatives of ent-kaurane steviol. Khaybullin RN, Strobykina IY, Dobrynin AB, et al. Bioorg. Med. Chem. Lett. 22(22), 6909-13, (2012)
Evaluation of steviol and its glycosides in Stevia rebaudiana leaves and commercial sweetener by ultra-high-performance liquid chromatography-mass spectrometry. Gardana C, Scaglianti M, and Simonetti P J. Chromatogr. A 1217(9), 1463-70, (2010)
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