H8664 Sigma

Steviol hydrate

≥98% (HPLC), powder

Synonym: (4α)-13-Hydroxykaur-16-en-18-oic acid hydrate


Related Categories Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Detection and Quantitation, Multi-Drug Resistance,
assay   ≥98% (HPLC)
form   powder
color   white to tan
solubility   DMSO: >10 mg/mL
storage temp.   2-8°C


Biochem/physiol Actions

Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters. Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. Steviol is a useful tool for studying renal drug clearance.

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