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H9523 Sigma

Serotonin hydrochloride

powder

Synonym: 3-(2-Aminoethyl)-5-hydroxyindole hydrochloride, 5-HT, 5-Hydroxytryptamine hydrochloride

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Properties

Related Categories Agonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology,
InChI Key   MDIGAZPGKJFIAH-UHFFFAOYSA-N
assay   ≥98%
form   powder
color   white
mp   149-154 °C(lit.)
solubility   H2O: soluble17 mg/mL
  0.1 M HCl: soluble22 mg/mL
  ethanol: soluble5.3 mg/mL
storage temp.   2-8°C
Gene Information   human ... HTR3A(3359)

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

Neurotransmitter.

Packaging

1 g in glass bottle

100, 250 mg in glass bottle

25 mg in poly bottle

Preparation Note

Solutions should be freshly prepared.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
NM2571000

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
Can I store solutions of Product H9523, Serotonin hydrochloride?
Solutions of this product are unstable.  We recommend preparing this solution fresh for each application.
Is Product H9523, Serotonin hydrochloride, the neurotransmitter serotonin?
This product is the neurotransmitter serotonin.  Other synonyms for this product are 3-(2-Aminoethyl)-5-hydroxyindole hydrochloride, 5-HT, and 5-Hydroxytryptamine hydrochloride.  More information on neurotransmitter synthesis can be found at:  http://www.sigmaaldrich.com/Area_of_Interest/Life_Science/PathFinder/Pathway_Maps/Biosynthesis_of_Neurotransmitters_.html
What are the storage conditions for Product H9523, Serotonin hydrochloride?
This product is a powder and should be refrigerated at 2-8°C. We do not recommend storing solutions of this product.
Has Product H9523, Serotonin hydrochloride, been cell culture tested?
No. We do not test this product for cell culture suitability.
What is the purity of Product H9523, Serotonin hydrochloride?
This product must be at least 98% pure according to our specifications.  The purity for individual lots can be found on the certificate of analysis.
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
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Protocols & Articles

Articles

History of Biogenic Amine Use for Treating Obesity

The discovery of ephedrine (Product No. E2750) in the 1930s led to the synthesis of amphetamines. Initially utilized as stimulants, they were soon shown to exhibit food intake and appetite suppressin...
Keywords: Obesity

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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