Anti-GP2 antibody produced in rabbit

Immunogen

Pancreatic secretory granule membrane major glycoprotein GP2 precursor recombinant protein epitope signature tag (PrEST)

General description

GP-2 is a membrane glycoprotein that is found in the secretory granules of the pancreatic exocrine components. This glycoprotein may modulate membrane transport in the acinar cells of the pancreas. GP-2 acts as an autoantigen in Crohn’s disease, thereby contributing to the pathogenesis of autoinflammatory responses associated with inflammatory bowel diseases ^1,2,3. Anti-GP2 antibody is specific for GP-2 in humans.

Physical form

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

Application

Anti-GP2 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using protein array and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.

Legal Information

Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC