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I0404 Sigma

Indirubin-3′-oxime

≥98% (HPLC), solid

Synonym: Indirubin-3′-monoxime

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Description

Biochem/physiol Actions

Indirubin-3′-oxime is a cyclin-dependent kinase inhibitor which functions by competing with ATP for binding to the catalytic subunit; exhibits antiproliferative activity leading to G2/M arrest in many cell lines and G1/S arrest in Jurkat cells.

Features and Benefits

This compound is featured on the CDKs and GSK-3 pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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RIDADR 
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WGK Germany 
3
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