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I1142 Sigma

Monoclonal Anti-Interferon-γ antibody produced in rat

clone 37895.11, purified immunoglobulin, lyophilized powder

Synonym: Anti-IFN-γ

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies against Cytokines/Growth Factors/Chemokines for Stem Cell Biology, Antibodies for Cell Biology, Antibodies for Hematopoietic Stem Cells,
species reactivity   mouse
application(s)   indirect ELISA: suitable
  neutralization: suitable
  western blot: suitable
clone   37895.11, monoclonal
antibody form   purified immunoglobulin
form   lyophilized powder
isotype   IgG2a
storage temp.   −20°C
Gene Information   mouse ... Ifng(15978)
biological source   rat
conjugate   unconjugated

Description

Immunogen

recombinant mouse IFN-γ.

General description

Interferon-γ (IFN-γ) belongs to Type II class of interferons and is produced by T helper cells (specifically, Th1 cells), natural killer (NK) and natural killer T (NKT) cells and cytotoxic T cells (TC cells) . It has various biological functions including antiviral activity like inhibition of cell or tumor growth, act as a potent modulator of immune responses and modifies cellular processes as well as stimulates the differentiation of B cells into immunoglobulin-producing cells. Monoclonal Anti-Interferon-γ antibody can be used in immunoblotting. Rat anti-Interferon-γ antibody has shown no cross-reactivity for recombinant human IFN-γ or recombinant rat IFN-γ.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Specificity

The antibody does not cross-react with recombinat human IFN-γ or recombinant rat IFN-γ.

Preparation Note

Purified from cell culture supernatant using protein G.

Application

Monoclonal Anti-Interferon-γ antibody can be used in neutralization and indirect ELISA.

Features and Benefits

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