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I122 Sigma

ICI 204,448 hydrochloride

solid

Synonym: (±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride, R,S-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl] phenoxy]-acetic acid hydrochloride

  • CAS Number 121264-04-8

  • Empirical Formula (Hill Notation) C23H26Cl2N2O4 · HCl

  • Molecular Weight 501.83

  •  MDL number MFCD00153814

  •  PubChem Substance ID 24278040

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   FNDGLVOYAQNQPE-UHFFFAOYSA-N
form   solid
color   white
solubility   45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble12 mg/mL
  dilute sodium carbonate: soluble4 mg/mL
  H2O: soluble4.5 mg/mL
Gene Information   human ... OPRK1(4986)

Description

Biochem/physiol Actions

κ opioid receptor agonist that does not cross the blood-brain barrier.

Packaging

25 mg in poly bottle

5 mg in glass bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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