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I1271 Sigma

LONG® R3 IGF-I human

recombinant, expressed in E. coli, Recombinant Analog, suitable for cell culture

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Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Application

LONG® R3 IGF-I is a recombinant analog of human insulin-like growth factor-I (IGF-I) that has been specifically engineered for the enhancement of cell culture performance. It is more biologically potent in vitro than either insulin or native IGF-I and has been shown to significantly increase recombinant protein production. It is ideal for both research and large-scale culture systems utilizing serum-free or low-level serum applications. LONG R3 IGF-I has been used with numerous cell types including CHO, vaccine-producing cell lines, fibroblasts and stem cells. All cell types that have a growth response to insulin in cell culture have the potential to respond to LONG R3 IGF-I. LONG R3 IGF-I provides equivalent or better performance to recombinant insulin depending on the cell line and clone.

LONG R3 IGF-I is produced in an Escherichia coli expression system without the use of animal-derived components.

Biochem/physiol Actions

A genetically engineered recombinant human analog of IGF-1.

Preparation Note

Lyophilized from 0.1M acetic acid

Legal Information

LONG is a registered trademark of Repligen Sweden AB

Price and Availability


Filter out uncertainty.

All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Insulin-like Growth Factors (IGF)

Insulin-like growth factors (IGF-I and IGF-II) are mitogenic and anabolic peptides structurally homologous to insulin. IGF-I and -II are single polypeptide chains of approximately 7.5 kDa comprised o...
Jennifer Fries
BioFiles 2009, 4.5, 12.
Keywords: Adhesion, Apoptosis, Biofiles, Cancer, Growth factors, Hormones, Infrared spectroscopy, Ligands, Transduction, transformation

Peer-Reviewed Papers
15

References

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