EMAIL THIS PAGE TO A FRIEND
I146 Sigma

IB-MECA

solid, ≥98% (HPLC)

Synonym: 1-Deoxy-1-[6-[((3-Iodophenyl)methyl)amino]-9H-purin-9-yl]-N-methyl-β-D-ribofuranuronamide, N6-(3-Iodobenzyl)adenosine-5′-N-methyluronamide

Purchase

Properties

Related Categories Adenosines/P2 Nucleotide Receptors (Purinergics), Agonists, Cell Biology, Cell Signaling and Neuroscience, Neuroscience,
InChI Key   HUJXGQILHAUCCV-MOROJQBDSA-N
assay   ≥98% (HPLC)
form   solid
color   white
solubility   ethanol: >10 mg/mL (hot)
  DMSO: >5 mg/mL
  H2O: insoluble
  aqueous acid: insoluble
  aqueous base: insoluble
storage temp.   2-8°C
Gene Information   human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)
rat ... Adora1(29290), Adora2a(25369), Adora3(25370)

Description

Packaging

5, 25 mg in glass bottle

Legal Information

Sold under license from the National Institutes of Health.

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Application

IB-MECA has been used for intraocular pressure and corneal thickness measurements in rabbits.

Biochem/physiol Actions

Selective A3 adenosine receptor agonist.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Fluorescent G protein-coupled receptors (GPCRs)

G protein-coupled receptors (GPCRs) are the largest class of transmembrane proteins and the targets for almost half of the clinical drugs in the market today. Advances in X-ray crystallography and ot...
Mike Earley, Market Segment Manager, Sigma Life Science
Biofiles Vol. 8, No. 4
Keywords: Clinical, Confocal microscopy, Ligands, Microscopy

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?