|Related Categories||Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones,|
|potency||≥25 units/mg (USP units)|
|suitability||suitable for cell culture|
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Insulin is used as a growth factor in many mammalian cell culture systems.
Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.
To prepare 10 mg/ml stock solution, add 10 ml of acidified H2O (pH ≤2) - prepared by addition of glacial acetic acid (approx. 0.1 ml).
powder-0 °C; solution stable 2-8 °C, 1 year
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Certificate of Analysis
Certificate of Origin
Development of a long-term serum-free culture system for immature granulosa cells from diethylstilboestrol-treated prepubertal rabbits: influence of androstenedione and fibronectin on FSH-induced cytodifferentiation Picazo, R., et al. Reproduction 119, 279-85, (2000)
The Effects of NPY and Insulin on Food Intake Regulation in Fish Silverstein, J.T., and Plisetskaya, E.M. Integr. Comp. Biol. 40, 296, (2000)
A Novel Purification Method For CNS Projection Neurons Leads To The Identification Of Brain Vascular Cells As A Source Of Trophic Support For Corticospinal Motor Neurons. Dugas, J.C., et al. J. Neurosci. 28, 8294-305, (2008)
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|I0516||Insulin solution from bovine pancreas, 10 mg/mL insulin in 25 mM HEPES, pH 8.2, BioReagent, sterile-filtered, suitable for cell culture|
|I9278||Insulin solution human, Chemically defined, recombinant from Saccharomyces cerevisiae, sterile-filtered, BioXtra, suitable for cell culture|
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