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I2250 Sigma

Indole-5-carboxylic acid

~95% (TLC)

Synonym: 5-Carboxyindole

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Properties

Related Categories Building Blocks, C7 to C9, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More...
InChI Key   IENZCGNHSIMFJE-UHFFFAOYSA-N
assay   ~95% (TLC)
mp   211-213 °C(lit.)
storage temp.   −20°C

Description

Application

• Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators
• Reactant for preparation of indolyl-quinolines via metal- and solvent-free autoxidative coupling reaction
• Reactant for preparation of anthranilic acids using bromamine-B oxidant and palladium chloride catalyst
• Reactant for synthesis of indirubin derivatives
• Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway
• Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
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I5400 Indole-5-carboxylic acid, 99%

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