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I2643 Sigma

Insulin human

recombinant, expressed in yeast (proprietary host)

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Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Packaging

25, 50, 250 mg in poly bottle

Application

Insulin human has been used:
• in the culture medium needed for the adipogenesis of ASCs (adipose-derived stem cells)
• to study the effect of insulin in the young and aged brains of rats.
• to study the effect of insulin on the inflammatory actions of protease-activated receptor 2 (PAR2) using mice model.

Biochem/physiol Actions

Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.

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All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
nwg
RTECS 
NM8900250

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Plasma Derived Proteins and Enzymes

Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Applications, Gas chromatography, Type

Peer-Reviewed Papers
15

References

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