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I2656 Sigma

Insulin-like Growth Factor-I (E3R) human

>95% (HPLC), recombinant, expressed in E. coli, lyophilized powder

Synonym: IGF-I (E3R)

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Description

Analysis Note

The biological activity is assayed using L6 myoblasts.

Biochem/physiol Actions

IGF1(3R) contains the amino acid substitution E3R, which decreases binding to IGF-binding proteins. IGF1(3R) therefore is much more potent than the native IFG1.

Physical form

Lyophilzed from a solution in 0.1 M acetic acid.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Huntington's Disease

Huntington's disease (HD) is an autosomal dominant, late-onset neurodegenerative disorder characterized by a selective neuronal cell death in the cortex and striatum leading to cognitive dysfunction,...
Carolyn L. Crankshaw
BioFiles v7 n2, 2011, 9–14
Keywords: Apoptosis, Huntington Disease, Transcription

Peer-Reviewed Papers
15

References

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