|Related Categories||Alphabetical Index, Antibodies, Antibodies against Cytokines/Growth Factors/Chemokines for Stem Cell Biology, Antibodies for Cell Biology, Antibodies for Hematopoietic Stem Cells,|
|indirect ELISA: suitable|
|western blot: 0.25-0.5 μg/mL using mouse interferon γ|
|antibody form||purified immunoglobulin|
|form||buffered aqueous solution|
|mol wt||antigen mol wt ~16 kDa|
|shipped in||dry ice|
|Gene Information||mouse ... Ifng(15978)|
purified recombinant mouse interferon γ.
Interferons (IFNs) are cytokines that are secreted in response to viral or bacterial infections and tumorigenesis. There are two types of IFNs, type I (IFN-α and IFN-β) and type II (IFN-γ). IFN-γ binds to specific receptor complex consisting of IFNγR1 and IFNγR2.1,2 There are many pathways that are mediated by IFN-γ binding such as JAK/STAT1, AP-1, NF-κB, STAT3 and STAT5.3,4 IFN-γ is pleotropic and performs various functions related to immune response, inflammation, differentiation and activation of T cells, cell cycle and apoptosis. The most studied function of IFN-γ is priming the antigen presenting cells by upregulating major histocompatibility (MHC) Class I molecules.1,4 IFN-γ has clinical applications in autoimmune diseases (rheumatoid arthritis), multiple sclerosis, cancer, HIV and fungal infections1,5
Anti-Interferon-γ recognizes amino acid residues 15-99 of mouse Interferon-γ.
Solution, 0.2 μm filtered, in 0.01 M phosphate buffered saline, pH 7.4.
The antibody recognizes an epitope between amino acid residues 15 and 99 of mouse interferon γ.
Anti-interferon-γ antibody may be used for immunoblotting at a working concentration of 0.25-0.5 μg/ml. The antibody is suitable for neutralization reactions, ELISA and immunoprecipitation.
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Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
5. Interferon-γ release assays for the diagnosis of latent tuberculosis infection in HIV-infected individuals-A systematic review and meta-analysis Cattamanchi A et al J. Acquir. Immune Defic. Syndr. 56, 230-8, (2011)
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|I8659||Anti-Interferon-γ antibody produced in goat, affinity isolated antibody, lyophilized powder|
|I9284||Monoclonal Anti-Interferon-γ antibody produced in mouse, clone 25723, purified immunoglobulin, lyophilized powder|
|I5521||Monoclonal Anti-Interferon-γ antibody produced in mouse, clone 25718, purified immunoglobulin, lyophilized powder|
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