• USA Home
  • I3525 - Interleukin-17A human

EMAIL THIS PAGE TO A FRIEND
I3525 Sigma

Interleukin-17A human

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, cell culture tested

Synonym: CTLA-8, IL-17

Purchase

Properties

Related Categories Cancer Research, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines & Growth Factors,
recombinant   expressed in E. coli
assay   ≥98% (SDS-PAGE)
form   lyophilized powder
impurities   endotoxin, tested (endotoxin level is less than 0.1 ng per μg cytokine (1 EU/μg).)
suitability   cell culture tested
storage temp.   −20°C
Gene Information   human ... IL17A(3605)

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Analysis Note

• The biological activity of human IL-17 is measured by its ability to induce IL-6 production using NHDF cells.
• Biological activity is also determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblast. The expected ED50 is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.

Physical form

Lyophilized with no additives.

Biochem/physiol Actions

IL-17, initially known as CTLA-8, is a T cell-expressed polypeptide that appears to be involved in the regulation of the hematopoietic system. IL-17 has been shown to induce IL-6, IL-8, and G-CSF production by fibroblasts; all of these cytokines have demonstrated effects on hematopoiesis.

Price and Availability


Discover the Milli-Q® IQ 7000 ultrapure water system
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?