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I4151 Sigma

Interferon β 1a human

≥95% (one N-glycosylation site), recombinant, expressed in CHO cells, solution, cell culture tested

Synonym: IFN-β 1a

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Properties

Related Categories Bioactives/Supplements, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones,
recombinant   expressed in CHO cells
assay   ≥95% (one N-glycosylation site)
form   solution
mol wt   mol wt ~23 kDa
impurities   endotoxin, tested
suitability   cell culture tested
shipped in   wet ice
storage temp.   2-8°C
Gene Information   human ... IFNB1(3456)

Description

Analysis Note

Biological activity is determined in a bioassay system against standard reference for human interferon-β by the inhibition of cytopathic effect in VERO cells challenged with vesicular stomatitis virus (VSV).

Physical form

Solution in 10 mM acetic acid.

Biochem/physiol Actions

Interferon-β is known to affect many important cell mediated immune responses, including enhanced expression of MHC molecules, β2-microglobulin, tumor associated antigens, and cytokine receptors for tumor necrosis factor, interleukin-1, interleukin-2, and colony stimulating factors. It is a potent endogenous inhibitor of angiogenesis.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
nwg
Protocols & Articles
Peer-Reviewed Papers
15

References

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