• USA Home
  • I4764 - IgG4, Lambda from human myeloma plasma

I4764 Sigma

IgG4, Lambda from human myeloma plasma

purified immunoglobulin, >95% (SDS-PAGE)

Synonym: Human IgG4-λ



Related Categories Antibodies, Human IgG Subclasses, Purified Immunoglobulins, Sera and Immunoglobulins, Supplementary Products More...
biological source   human
antibody form   purified immunoglobulin
assay   >95% (SDS-PAGE)
conjugate   unconjugated
shipped in   dry ice
storage temp.   −20°C


Analysis Note

The purity and identity are determined by immunoelectrophoresis, indirect ELISA, and SDS-PAGE.


Purified IgG4 λ from human.

Physical form

Solution in 0.02 M Tris buffered saline, pH 8.0.


The purified IgG4, λ may be used as an immunoglobulin calibrator, reference antigen, blocking agent, or coating protein in a variety of immunoassays including ELISA, dot blot immunobinding, Western immunobloting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell binding assays. Purified IgG4, λ was used as isotype control in flow cytometry of chronic lymphocytic leukemia and mantle cell lymphoma cells. It was also used for lectin- surface plasmon resonance and IgG subclass labelling by flow cytometry at a concentration of 50 μg/ml.

General description

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. IgG4 is the least abundant of the IgG subclass. IgG4-related systemic diseases include autoimmune pancreatitis, mediastinal fibrosis and multiple sclerosis
Human myeloma IgG4, λ is purified from human plasma by fractionation, ion-exchange, and affinity chromatography procedures.

Price and Availability

Antibody Explorer

Explore with Confidence

Amplified Detection
Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis

Certificate of Origin

Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers


Related Products

related product

Product #


Add to Cart

06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?