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I4902 Sigma

Anti-Interferon-α/β Receptor 1 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym: Anti-IFN-α/β R1

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Description

Immunogen

recombinant human IFN-α/β R1 extracellular domain expressed in Sf21 insect cells.

General description

Interferon-α/β Receptor 1 is a dimeric, disulfide-linked protein that binds human interferons α and β. This receptor also interacts with Tyr kinase JAK1, and thereby regulates cellular signaling across the membranes . Anti-Interferon-α/β Receptor 1 is specific for recombinant human IFN-α/β R1 and does not react with recombinant human IFN-γ RI and IFN-γ RII.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Application

Anti-Interferon-α/β Receptor 1 antibody is suitable for use in flow cytometry (3-10 μg/test) and western blot (0.1-0.2 μg/mL). The antibody may also be used for immunoblotting (approx. 135kDa) and indirect immunofluorescence (using appropriate secondary antibodies).

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  1
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