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I5271 Sigma

Interleukin-1β from mouse

IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym: IL-1β, Lymphocyte activating factor

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Description

Analysis Note

The biological activity is measured by the dose-dependent stimulation of murine D10G4.1 cells.

Other Notes

The two closely related agents, Interleukin-1α (IL-1α) and Interleukin-1β (IL-1β) bind to the same cell surface receptor, elicit nearly identical biological responses and yet share 25% homology in their amino acid sequence.

Physical form

Lyophilized from 0.2 μm filtered solution in 10mM Sodium Citrate, pH 4.0

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Interleukin Family (IL)

The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages...
Jennifer Fries
BioFiles 2009, 4.5, 16.
Keywords: Anti-inflammatory agents, Antitumor agents, Cancer, Cell proliferation, Gene expression, Growth factors, Transcription

Peer-Reviewed Papers
15

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