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  • I5652 - Monoclonal Anti-Interleukin-2 Soluble Receptor α antibody produced in mouse

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I5652 Sigma

Monoclonal Anti-Interleukin-2 Soluble Receptor α antibody produced in mouse

clone 22722, purified immunoglobulin, lyophilized powder

Synonym: Anti-IL-2 sRα

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Description

Immunogen

recombinant human IL-2 soluble receptor alpha (IL-2 Rα), expressed in Sf 21 insect cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline wth 5% trehalose.

Preparation Note

Purified using protein A.

Biochem/physiol Actions

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. The effects of IL-2 are mediated by the signaling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signaling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle.

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Safety & Documentation

Documents

Certificate of Analysis

Certificate of Origin

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
Protocols & Articles

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Peer-Reviewed Papers
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References

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