• USA Home
  • I5902 - Monoclonal Anti-Interleukin-2 Soluble Receptor γ antibody produced in mouse

EMAIL THIS PAGE TO A FRIEND
I5902 Sigma

Monoclonal Anti-Interleukin-2 Soluble Receptor γ antibody produced in mouse

clone 38024.11, purified immunoglobulin, lyophilized powder

Synonym: Anti-IL-2 sRγ

Purchase

Description

Immunogen

mouse cells transfected with human IL-2 soluble receptor γ.

General description

Interleukin-2 Receptor γ is a 64kD protein, that form complex with its β chain for IL-2 internalization and cell activation. It expresses in many cell types including neutrophils, thymocytes, CD4+ and CD8+ T cells, B cells, NK cells and monocytes. Mutation in IL2RG can leads to X-linked severe combined immunodeficiency (SCID) . Monoclonal anti-Interleukin-2 Soluble Receptor γ antibody can be used to block biological activity facilitated by IL-2. It can also be used for neutralizing the biological activity of IL-2 R γ. Mouse anti-Interleukin-2 Soluble Receptor γ antibody reacts specifically with human IL-2 soluble receptor γ. The product has shown no cross-reactivity with recombinant human IL-2 R α, IL-2 R β, IL-1 RI, IL-1 RII, IL-4 R, IL-6 R, IL-7 R and IL-10 R.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Preparation Note

Purified using protein G.

Application

Monoclonal anti-Interleukin-2 Soluble Receptor γ antibody can be used in immunoblotting and ELISA for detecting IL-2 R γ.

Analysis Note

The antibody will neutralize human cell surface IL-2 Rγ mediated-bioactivity.

Price and Availability


Antibody Explorer

Explore with Confidence

All labs need water
Safety & Documentation

Safety Information

WGK Germany  3
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?