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  • I7026 - Anti-Insulin-like Growth Factor Binding Protein-4 antibody produced in goat

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I7026 Sigma

Anti-Insulin-like Growth Factor Binding Protein-4 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym: Anti-IGFBP-4

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Antibodies to Cytokines and Growth Factors,
species reactivity   human
application(s)   indirect ELISA: 0.5-1.0 μg/mL
  neutralization: suitable
  western blot: 0.1-0.2 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   human ... IGFBP4(3487)
biological source   goat
conjugate   unconjugated

Description

Immunogen

purified, NSO-derived, recombinant human insulin-like growth factor binding protein 4.

General description

Insulin-like growth factor binding protein-4 (IGFBP-4) is a 26kD (approx.) protein expressed highly in non-paranchymal cells of the liver. IGFBP-4 is also expressed in spleen, liver, lung, kidney, adrenal, testis, heart, brain cortex, stomach and hypothalamus. It has a pivotal role in protecting cells from overstimulation caused by IGFs or towards activating the alternate transmembrane signaling pathways that are inhibited by IGF exposure. Anti-Insulin-like Growth Factor Binding Protein 4(IGFBP-4) antibody can be used in western blotting. Goat anti-IGFBP-4 antibody reacts specifically with recombinant human IGFBP-4. The product has shown no cross-reactivity for recombinant human IGFBP-1, recombinant human IGFBP-2, recombinant human IGFBP-3, recombinant human IGFBP-5 and recombinant human IGFBP-6.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.

Specificity

By immunoblotting and ELISA, the antibody show no cross-reactivity with recombinant human IGFBP-2, recombinant human IGFBP-3, recombinant human IGFBP-1, recombinant human IGFBP-5, and recombinant human IGFBP-6.

Application

Anti-Insulin-like Growth Factor Binding Protein-4(IGFBP-4) antibody can be used in neutralization and indirect ELISA.

Price and Availability


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