• USA Home
  • I7784 - Anti-Interleukin-2 antibody produced in goat

EMAIL THIS PAGE TO A FRIEND
I7784 Sigma

Anti-Interleukin-2 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym: Anti-IL-2

Purchase

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Cytokines and Growth Factors, Antibodies to Interleukins (IL),
species reactivity   mouse, rat
application(s)   neutralization: suitable
  western blot: 0.1-0.2 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   mouse ... Il2(16183)
rat ... Il2(116562)
biological source   goat
conjugate   unconjugated

Description

Immunogen

purified, E. coli-derived recombinant mouse interleukin-2.

General description

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signalling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signalling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle
Monoclonal Anti-Interleukin-2 recognizes murine Interleukin-2. It does not react with human IL-2, but will react with rabbit IL-2 at a 100x higher IgG concentration.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Application

Anti-interleukin-2 antibody may be used for immunoblotting at a working concentration of 0.1-0.2 μg/ml. The antibody is suitable for murine IL-2 neutralization assays.

Price and Availability


Antibody Explorer

Explore with Confidence

All labs need water
Safety & Documentation

Safety Information

Personal Protective Equipment  Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  1
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

I8273 Anti-Interleukin-2 antibody produced in goat, IgG fraction of antiserum, lyophilized powder
I6784 Monoclonal Anti-Interleukin-2 antibody produced in mouse, clone 5334, purified immunoglobulin, lyophilized powder
I6909 Monoclonal Anti-Interleukin-2 antibody produced in mouse, clone 5355, purified immunoglobulin, lyophilized powder
I8398 Anti-Interleukin-2 antibody produced in goat, IgG fraction of antiserum, lyophilized powder
I7401 Anti-Interleukin-2 antibody produced in goat, affinity isolated antibody, lyophilized powder

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?