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  • I7892 - Anti-Interferon-γ Inducible Protein antibody produced in goat

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I7892 Sigma

Anti-Interferon-γ Inducible Protein antibody produced in goat

IgG fraction of antiserum, lyophilized powder

Synonym: Anti-IP-10

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Chemokines, Antibodies to Cytokines and Growth Factors,
species reactivity   human
application(s)   indirect ELISA: suitable
  western blot: suitable
clone   polyclonal
antibody form   IgG fraction of antiserum
form   lyophilized powder
storage temp.   −20°C
Gene Information   human ... CXCL10(3627)
biological source   goat
conjugate   unconjugated

Description

Immunogen

recombinant human IP-10.

General description

Interferon-γ Inducible Protein (IP-10), also known as CXCL-10, is a cytokine that belongs to the CXC chemokine family. It is secreted in response to interferon-γ by neutrophils, monocytes, basophils, epithelial cells and keratinocytes. IP-10 is involved in chemotaxis, apoptosis, angiostasis and inhibits cell growth. The effects of IP-10 are mediated by its receptor, CXCR3. The major signalling pathways that are activated by IP-10 are those of MAPK, PKA, JNK, NF-κB and PI3K/Akt. Alteration of IP-10 levels has been observed in various infectious diseases caused bacteria, fungi and viruses such as dengue, Ebola and hepatitis B
Anti-Interferon-γ Inducible Protein antibody detects human IP-10.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose

Preparation Note

Purified using protein G.

Application

Anti-Interferon-γ Inducible Protein antibody may be used for immunoblotting at a working antibody concentration of 1-2 μg/ml. For ELISA, antibody concentration of 0.5-1.0 μg/ml is recommended.

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Safety & Documentation

Documents

Certificate of Analysis

Certificate of Origin

Safety Information

Personal Protective Equipment  Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  2
Protocols & Articles

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Peer-Reviewed Papers
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References

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