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I7904 Sigma

Indomethacin heptyl ester

methyl acetate solution, ≥98% (HPLC)

  • Empirical Formula (Hill Notation) C26H30ClNO4

  • Molecular Weight 455.97

  •  EC Number 201-185-2

  •  MDL number MFCD03412025

  •  PubChem Substance ID 329815317

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Description

Application

Used to inhibit COX-1 and COX-2. To achieve 50% inhibition of human recombinant COX-2 use I7904 at 0.04 uM/mL .

Biochem/physiol Actions

Potent cyclooxygenase-2 inhibitor. 1700 times greater activity against COX-2 than COX-1.

Other Notes

Derivatized indomethacin.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Supplemental Hazard Statements 
Repeated exposure may cause skin dryness or cracking.
RIDADR 
UN1231 - class 3 - PG 2 - Methyl acetate, solution
WGK Germany 
3
Flash Point(F) 
8.6 °F
Flash Point(C) 
-13 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
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