• USA Home
  • I9029 - Insulin-like Growth Factor Binding Protein-6 human

EMAIL THIS PAGE TO A FRIEND
I9029 Sigma

Insulin-like Growth Factor Binding Protein-6 human

>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym: IGFBP-6

Purchase

Properties

Related Categories Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones,
recombinant   expressed in NSO cells
assay   >97% (SDS-PAGE)
form   lyophilized powder
mol wt   calculated mol wt 23 kDa
  mol wt 34 kDa by SDS-PAGE (reducing)
impurities   endotoxin, tested
storage temp.   −20°C
Gene Information   human ... IGFBP6(3489)

Description

Analysis Note

The biological activity is measured by its ability to inhibit the biological activity of recombinant human IGF-II on MCF-7 cells.

Biochem/physiol Actions

Insulin-like growth factor binding protein found in cerebrospinal fluid and serum; exhibits 2-fold higher affinity for IGF-II than for IGF-I.

IGFBP-6 (insulin-like growth factor binding protein-6) works as a tumor suppressor for nasopharyngeal carcinoma and also suppresses prostate cancer cell proliferation.

Packaging

25 μg in glass bottle

Physical form

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% TFA.

General description

The gene IGFBP-6 (insulin-like growth factor binding protein-6) is mapped to human chromosome 12q13.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?