• USA Home
  • I9404 - Interleukin-10/Fc Chimera (non-lytic) human

EMAIL THIS PAGE TO A FRIEND
I9404 Sigma

Interleukin-10/Fc Chimera (non-lytic) human

>98% (SDS-PAGE), recombinant, expressed in NS.1 cells, buffered aqueous solution

Synonym: IL-10:Fc (non-lytic) human

Purchase

Properties

Related Categories Cancer Research, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines & Growth Factors,
recombinant   expressed in NS.1 cells
assay   >98% (SDS-PAGE)
form   buffered aqueous solution
mol wt   mol wt 98 kDa
impurities   endotoxin, tested
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... IL10(3586)

Description

Biochem/physiol Actions

Possesses the biological function of the IL-10 moiety and a prolonged circulating half-life determined by the Fc domain.

IL-10 (interleukin-10) is an anti-inflammatory cytokine. High levels of IL-10 are present in late syphilis. It suppresses Th1 (T helper) cytokines. IL-10 also controls the differentiation and proliferation of T cells, B cells, natural killer cells, antigen-presenting cells and mast cells.

Other Notes

Dimeric fusion protein consisting of human IL-10 fused to mutant human IgG1 Fc.

Physical form

Solution in 0.2 μm filtered phosphate buffered saline, pH 7.4.

General description

The gene IL-10 (interleukin-10) is mapped to human chromosome 1q31-32. It is secreted by monocytes and lymphocytes.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?