• USA Home
  • I9905 - Interleukin-2/Fc Chimera (non-lytic) from mouse

EMAIL THIS PAGE TO A FRIEND
I9905 Sigma

Interleukin-2/Fc Chimera (non-lytic) from mouse

>98% (SDS-PAGE), recombinant, expressed in CHO cells, solution

Synonym: IL-2:Fc (non-lytic)

Purchase

Description

Analysis Note

The biological activity is measured in a cell proliferation assay using CTLL2 cells.

Biochem/physiol Actions

Possesses the biological functions of the IL-2 moiety and a prolonged circulating half-life determined by the Fc domain.

IL-2 (interleukin-2) is a cytokine which is involved in the differentiation of T cell and natural killer (NK) cell, T cell memory, activation-induced lymphocyte cell death. The protein also has a role in regulatory T cell (Treg) development and homeostasis. It is linked with the risk of Grave′s disease, rheumatoid arthritis, celiac disease, multiple sclerosis, psoriasis, Crohn′s disease, ulcerative colitis and type-1 diabetes (T1D).

Other Notes

Dimeric fusion protein consisting of mouse IL-2 fused to mutant mouse IgG2a Fc.

Physical form

Solution in 0.2 μm filtered phosphate buffered saline, pH 7.4.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?