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K1757 Sigma

Keratinocyte Growth Factor human

KGF, recombinant, expressed in E. coli, powder, suitable for cell culture

Synonym: FGF-7, KGF, hFGF-7, hKGF

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Properties

Related Categories Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones,
recombinant   expressed in E. coli
assay   ≥95% (SDS-PAGE and HPLC)
form   powder
potency   1.0-10 ng/mL ED50/EC50
quality   endotoxin tested
suitability   suitable for cell culture
storage temp.   −20°C

Description

Analysis Note

The proliferative activity is tested in culture using the murine hematopoietic cell line BaF3.

Biochem/physiol Actions

Keratinocyte growth factor (KGF, 18.9 kDa, 163 amino acids) includes a secretory signal sequence and shares 39% identity with FGF-Basic. It is expressed in a number of stromal fibroblast cell lines but absent from normal glial cells and epithelial cell lines. KGF stimulates proliferation and differentiation of keratinocytes and other cells in the epithelium and induces chemotaxis of microvascular endothelial cells and neovascularization of rat cornea.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin.

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Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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