|Related Categories||Alphabetical Index, Antibodies, Antibodies for Parkinson’s Disease Research, Antibodies in Array, Cell Biology,|
|application(s)||western blot: 1-2 μg/mL using HEK-293T cells expressing human LRRK2|
|antibody form||affinity isolated antibody|
|form||buffered aqueous solution|
|mol wt||antigen mol wt ~240 kDa|
|shipped in||dry ice|
human ... LRRK2(120892)|
mouse ... Lrrk2(66725)
rat ... (300160)
synthetic peptide corresponding to amino acids 2512-2527 of human LRRK2 conjugated to KLH. The corresponding sequence is highly conserved (~80% identity) in mouse and rat LRRK2.
LRRK2 is a μLtimeric kinase that also functions as a GTPase. LRRK2 activates a CaMKK-β/AMPK signaling pathway and subsequently mediates autophagy. Genetic alterations in LRRK2 cause late-onset Parkinson′s disease 1,2. Anti-LRRK2 (C-terminal) antibody is specific for human LRRK2 (approx. 240 kDa). Staining of the LRRK2 band by immunoblotting is specifically inhibited by the LRRK2 immunizing peptide.
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Anti-LRRK2 (C-terminal) antibody is suitable for use in western blot (1-2 μg/mL using HEK-293T cells expressing human LRRK2).
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Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
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|L9918||Anti-LRRK2 (C-terminal region) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution|
|L3044||Monoclonal Anti-LRRK2 antibody produced in mouse, ~1.0 mg/mL, clone PROK57, purified immunoglobulin, buffered aqueous solution|
|WH0120892M1||Monoclonal Anti-LRRK2 antibody produced in mouse, clone 3B2, purified immunoglobulin, buffered aqueous solution|
|HPA014293||Anti-LRRK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution|
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