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  • L1636 - L-Leucine chloromethyl ketone hydrochloride

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L1636 Sigma

L-Leucine chloromethyl ketone hydrochloride

Synonym: Leu-CMK HCl

  • CAS Number 54518-92-2

  • Empirical Formula (Hill Notation) C7H14ClNO · HCl

  • Molecular Weight 200.11

  •  MDL number MFCD00238011

  •  PubChem Substance ID 24896287

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Properties

Related Categories Amino Acids, Biochemicals and Reagents, I - Z, Modified Amino Acids
InChI Key   DRZZRBOLWKRHPF-RGMNGODLSA-N

Description

Biochem/physiol Actions

L-Leucine chloromethyl ketone (Leu-CMK) is used as a lysosomal cysteine protease inhibitor and as an insulin-like stimulator of lipid synthesis. L-Leucine chloromethyl ketone (Leu-CMK) may be acetylated to generate acetylleucine chloromethyl ketone, an inhibitor of acylpeptide hydrolase.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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