|Related Categories||Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics G-M, Biochemicals and Reagents,|
|potency||800-900 units per mg|
|suitability||suitable for cell culture|
Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA.1
Mode of action: inhibits bacterial protein synthesis
Antimicrobial spectrum: Gram-positive bacteria
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Certificate of Origin
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi|
|Risk Statements (Europe)||36/37/38|
|Safety Statements (Europe)||26|
Protein synthesis is a complex, multi-step process involving many enzymes as well as conformational alignment. However, the majority of antibiotics that block bacterial protein synthesis interfere wi...
BioFiles 2006, 1.4, 17.
Keywords: Antibiotics, Environmental, Peptide synthesis
[Functional state of the ileum, cationic peptids and zinc content in the Paneth cells of the rats following lincomycin, indomethacin and methotrexate andministration]. Horokhovs'kyĭ IeIu, Ieshchenko IuV, Bovt VD, et al. Fiziol. Zh. 59(3), 78-88, (2013)
A multicentric, open label, randomised, postmarketing efficacy study comparing multidose of lincomycin hydrochloride capsule 500 mg with multidose cefpodoxime proxetil tablet 200 mg in patients with tonsillitis, sinusitis. Kothadiya A J. Indian Med. Assoc. 110(8), 580-3, (2012)
Construction of the octose 8-phosphate intermediate in lincomycin A biosynthesis: characterization of the reactions catalyzed by LmbR and LmbN. Sasaki E, Lin CI, Lin KY, et al. J. Am. Chem. Soc. 134(42), 17432-5, (2012)
Identification of novel vga(A)-carrying plasmids and a Tn5406-like transposon in meticillin-resistant Staphylococcus aureus and Staphylococcus epidermidis of human and animal origin. Lozano C, Aspiroz C, Rezusta A, et al. Int. J. Antimicrob. Agents 40(4), 306-12, (2012)
Higher plant photosystem II light-harvesting antenna, not the reaction center, determines the excited-state lifetime-both the maximum and the nonphotochemically quenched. Belgio E, Johnson MP, Jurić S, et al. Biophys. J. 102(12), 2761-71, (2012)
Gene expression of ribosomal protein mRNA in Chironomus riparius: effects of endocrine disruptor chemicals and antibiotics. Park K and Kwak IS Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 156(2), 113-20, (2012)
Deactivation processes in PsbA1-Photosystem II and PsbA3-Photosystem II under photoinhibitory conditions in the cyanobacterium Thermosynechococcus elongatus. Ogami S, Boussac A, and Sugiura M Biochim. Biophys. Acta 1817(8), 1322-30, (2012)
Optimisation and validation of a quantitative and confirmatory method for residues of macrolide antibiotics and lincomycin in kidney by liquid chromatography coupled to mass spectrometry. Rezende CP, Souza LF, Almeida MP, et al. Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 29(4), 587-95, (2012)
Decontamination of mycoplasma-contaminated Orientia tsutsugamushi strains by repeating passages through cell cultures with antibiotics. Ogawa M, Uchiyama T, Satoh M, et al. BMC Microbiol. 13, 32, (2013)
Long-term observations on the dynamics of bovine digital dermatitis lesions on a California dairy after topical treatment with lincomycin HCl. Berry SL, Read DH, Famula TR, et al. Vet. J. 193(3), 654-8, (2012)
Effect of chronic exposure to acetaminophen and lincomycin on Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moina macrocopa, and potential mechanisms of endocrine disruption. Kim P, Park Y, Ji K, et al. Chemosphere 89(1), 10-8, (2012)
Analysis of sub μg/kg lincomycin in honey, muscle, milk, and eggs using fast liquid chromatography-tandem mass spectrometry. Tölgyesi A, Fekete J, Fekete S, et al. J. Chromatogr. Sci. 50(3), 190-8, (2012)
Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics Champney, W.S. and Tober, C.L. Curr. Microbiol. 41, 126-135, (2000)
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