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L2792 Sigma

LCK, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym: YT16, p56lck, pp58lck

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Properties

Related Categories Active Kinases, Application Index, Biochemicals and Reagents, Cancer Research, Cancer Research Enzymes,
recombinant   expressed in baculovirus infected Sf9 cells
grade   PRECISIO® Kinase
assay   ≥70% (SDS-PAGE)
form   buffered aqueous glycerol solution
activity   180-244 nmol/min·mg
mol wt   mol wt ~84 kDa
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... LCK(3932)

Description

Biochem/physiol Actions

Tyrosine kinase that activates T-lymphocytes.

LCK (proto-oncogene) belongs to the Src family of kinase and is mainly expressed in T cells. It is important for T cell development and homeostasis. LCK is upregulated in acute and chronic leukemias, colorectal and prostate cancers.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Protocols & Articles
Peer-Reviewed Papers
15

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