Lipoteichoic acid from Bacillus subtilis
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CAS Number 56411-57-5
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MDL number MFCD00131526
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Popular Documents: Specification Sheet (PDF)
Properties
| Related Categories | Biochemicals and Reagents, Complex Lipids, Glycerolipid Metabolism, Glycolipids, Lipids, |
| storage temp. | 2-8°C |
Description
Biochem/physiol Actions
Lipoteichoic acid (LTA) is a complex component of cell walls of Gram-positive bacteria that are involved in a wide range of cell processes such as the stimulation of immune responses and cell signaling pathways. LTA differs between species of gram-positive bacteria. Lipoteichoic acid from Bacillus subtilis may be used to compare its structure, immunogenicity and functions versus other bacterial LTAs.
Lipoteichoic acid (LTA) is a teichoic acid attached to a lipid abundant on Gram-positive bacteria cell wall. LTA is a pathogen-associated molecular-patterns (PAMP) recognized by Toll-like receptor 2 (TLR2), This recognition leads to the activation of NF-kB.
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