|Related Categories||Biochemicals and Reagents, Complex Lipids, Glycerolipid Metabolism, Glycolipids, Lipids,|
Lipoteichoic acid (LTA) is a complex component of cell walls of Gram-positive bacteria that are involved in a wide range of cell processes such as the stimulation of immune responses and cell signaling pathways. LTA differs between species of gram-positive bacteria. Lipoteichoic acid from Bacillus subtilis may be used to compare its structure, immunogenicity and functions versus other bacterial LTAs.
Lipoteichoic acid (LTA) is a teichoic acid attached to a lipid abundant on Gram-positive bacteria cell wall. LTA is a pathogen-associated molecular-patterns (PAMP) recognized by Toll-like receptor 2 (TLR2), This recognition leads to the activation of NF-kB.
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Intrinsic nitric oxide-stimulatory activity of lipoteichoic acids from different Gram-positive bacteria. Zídek Z, Farghali H, Kmoníčková E. Nitric Oxide 232, 300-310, (2010)
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