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L3908 Sigma

β-Lactoglobulin from bovine milk

≥90% (PAGE), lyophilized powder



Related Categories Biochemicals and Reagents, Casein and Other Milk Proteins, Proteins and Derivatives More...
assay   ≥90% (PAGE)
form   lyophilized powder
storage temp.   2-8°C


Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Other Notes

Contains β-lactoglobulins A and B which can be isolated chromatographically.


1, 5 g in poly bottle

250 mg in poly bottle

Preparation Note

Chromatographically purified


May not contain folate binding protein; not recommended for folate analysis.


β-Lactoglobulin was used in a cytologic assay for diagnosis of food hypersensitivity in patients with irritable bowel syndrome.

Biochem/physiol Actions

A member of the lipocalin family, βLg is a small protein of 162 amino acids with a molecular mass of ∼18,400 Da. It features an eight-stranded β-barrel (strands A-H) succeeded by a three-turn a-helix and a final β-strand (strand I) that forms part of the dimerization interface.

General description

Milk from dairy cows contains the protein β-lactoglobulin (BLG). It naturally occurs in a number of genetic variants, and the most prevalent bovine variants are BLG A and BLG B.

Price and Availability

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

How does the storage temperature relate to shipping conditions?
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. http://www.sigmaaldrich.com/etc/medialib/docs/Sigma-Aldrich/General_Information/shippingandlong-termstoragev3.Par.0001.File.tmp/shippingandlong-termstoragev3.pdf
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
What is the molecular weight of Product L3908, β-Lactoglobulin from bovine milk?  
Product L3908, β-Lactoglobulin from bovine milk, exists as a dimer of two peptides. Peptide A = 18,367, B = 18,281; the monomer is approximately 36,600.
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Protocols & Articles


Monitoring the Formation of PEGylated Protein (ß-Lactoglobulin) Reaction Products by HPLC using TSKgel® SP-STAT

From our library of Articles, Sigma-Aldrich presents Monitoring the Formation of PEGylated Protein (ß-Lactoglobulin) Reaction Products by HPLC using TSKgel® SP-STAT
Keywords: Chromatography, High performance liquid chromatography

Peer-Reviewed Papers


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