EMAIL THIS PAGE TO A FRIEND
L4021 Sigma

Prolactin human

recombinant, expressed in E. coli, lyophilized powder, BioReagent, cell culture tested, >97% (SDS-PAGE)

Synonym: LTH, Lactogenic Hormone, Luteotropic Hormone, PRL, hPRL

Purchase

Properties

Related Categories Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones,
recombinant   expressed in E. coli
description   200 amino acid residue methionyl form of mature, recombinant human prolactin (amino acid residues 29-227).
product line   BioReagent
assay   >97% (SDS-PAGE)
form   lyophilized powder
mol wt   predicted mol wt ~24 kDa
impurities   endotoxin, tested
suitability   cell culture tested
storage temp.   −20°C
Gene Information   human ... PRL(5617)

Description

Analysis Note

The biological activity is assayed by proliferation of the rat lymphoma cell line, Nb2-11.

Application

Use in cell culture applications to study prolactin regulation of cell signaling and gene expression.

Other Notes

Contains an N-terminal methionine not present in the natural product.

Reconstitution

It is recommended that sterile 4 mM HCl containing 1 mg/mL bovine serum albumin be added to the vial to prepare a stock solution of no less than 10 mg/mL.

Physical form

Lyophilized from a solution in 10 mM phosphate and 50 mM sodium chloride, pH 8.0.

Biochem/physiol Actions

Prolactin is a neuroendocrine hormone. The prolactin receptor is a transmembrane glycoprotein that belongs to the cytokine hematopoietic receptor family. A large number of cells and organs express the receptor, including B cells, T cells, macrophages, monocytes, and neutrophils. Prolactin signal transduction involves the JAK/STAT families and the src kinase family. Induces lactation; inhibits secretion of gonadotropins; release is inhibited by dopamine.

Price and Availability


Filter out uncertainty.
Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?