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L4913 Sigma

[His(3-Methyl)2]-LH-RH

>96% (HPLC)

Synonym: [His(π-Methyl)2]-LH-RH

  • CAS Number 38343-58-7

  • Empirical Formula (Hill Notation) C56H77N17O13

  • Molecular Weight 1196.32

  •  MDL number MFCD03452956

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, LH-RH, Neuropeptides, Peptides and Proteins,
assay   >96% (HPLC)
mol wt   mol wt 1196.33
storage temp.   −20°C
Gene Information   human ... GNRH1(2796)

Description

Amino Acid Sequence

Glp-His(Me)-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

Biochem/physiol Actions

GnRH (gonadotropin-releasing hormone) (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.

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Safety & Documentation

Safety Information

WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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