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L6038 Sigma

LH-RH Fragment 1-4

>98% (HPLC)

  • Empirical Formula (Hill Notation) C25H29N7O7

  • Molecular Weight 539.54

  •  MDL number MFCD03452958

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, LH-RH, Neuropeptides, Peptides and Proteins,
InChI Key   FMJXVANOHHICFP-LEAZDLGRSA-N
assay   >98% (HPLC)
storage temp.   −20°C
Gene Information   human ... GNRH1(2796), GNRHR(2798)
mouse ... GNRH1(14714), GNRHR(14715)
rat ... GNRH1(25194), GNRHR(81668)

Description

Amino Acid Sequence

Glp-His-Trp-Ser

Biochem/physiol Actions

Glp-His-Trp-Ser is fragment 1-4 of GnRH (gonadotropin-releasing hormone). GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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