|Related Categories||Analytical and Industrial Enzymes, Biochemicals and Reagents, Chemiluminescent compounds, Enzyme Substrates, Enzymes, Inhibitors, and Substrates,|
Substrate for firefly luciferase with a Km of approx 2 μM.
Highly purified grade with reduced levels of inhibitor relative to L 9504
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lyophilized powder, synthetic
BioUltra, lyophilized powder, ≥98% (SDS-PAGE), 15-30×106 light units/mg protein
Chemotherapy is the treatment of choice against many types of cancer. However, over time chemotherapeutic drugs can become less effective due to the development of resistance that involves a group of...
BioFiles 2007, 2.4, 7.
Keywords: Absorption, Cancer, Clinical, Cloning, Combinatorial synthesis, Diseases, Enzymology, Gene expression, Genetic, Immunology, Pharmaceutical, Reductions, Transfection
Transcriptional activity of the murine retinol-binding protein gene is regulated by a multiprotein complex containing HMGA1, p54 nrb/NonO, protein-associated splicing factor (PSF) and steroidogenic factor 1 (SF1)/liver receptor homologue 1 (LRH-1). Bianconcini A, Lupo A, Capone S, et al. Int. J. Biochem. Cell Biol. 41(11), 2189-203, (2009)
In vivo imaging reveals selective PPAR activity in the skin of peroxisome proliferator-activated receptor responsive element-luciferase reporter mice. El-Jamal N, Dubuquoy L, Auwerx J, et al. Exp. Dermatol. 22(2), 137-40, (2013)
A transcriptional survey of the cDNA library of Macrolampis sp2 firefly lanterns (Coleoptera: Lampyridae). Viviani VR, Carmargo IA, and Amaral DT Comp. Biochem. Physiol. Part D. Genomics Proteomics 8(1), 82-5, (2013)
Spectroscopic studies of the color modulation mechanism of firefly (beetle) bioluminescence with amino-analogs of luciferin and oxyluciferin. Hirano T, Nagai H, Matsuhashi T, et al. Photochem. Photobiol. Sci. 11(8), 1281-4, (2012)
The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection. Alsaadi M, Italia JL, Mullen AB, et al. J. Control. Release 160(3), 685-91, (2012)
The location and nature of general anesthetic binding sites on the active conformation of firefly luciferase; a time resolved photolabeling study. Shanmugasundararaj S, Lehle S, Yamodo HI, et al. PLoS ONE 7(1), e29854, (2012)
A route from darkness to light: emergence and evolution of luciferase activity in AMP-CoA-ligases inferred from a mealworm luciferase-like enzyme. Viviani VR, Prado RA, Neves DR, et al. Biochemistry 52(23), 3963-73, (2013)
Strengths and weaknesses in the determination of Saccharomyces cerevisiae cell viability by ATP-based bioluminescence assay. Paciello L, Falco FC, Landi C, et al. Enzyme Microb. Technol. 52(3), 157-62, (2013)
Efficient firefly chemi/bioluminescence: evidence for chemiexcitation resulting from the decomposition of a neutral firefly dioxetanone molecule. Pinto da Silva L, Santos AJ, and Esteves da Silva JC J. Phys. Chem. A 117(1), 94-100, (2013)
Measurements of vaccinia virus dissemination using whole body imaging: approaches for predicting of lethality in challenge models and testing of vaccines and antiviral treatments. Zaitseva M, Kapnick S, and Golding H Methods Mol. Biol. 890, 161-76, (2012)
Definition of metabolism-dependent xenobiotic toxicity with co-cultures of human hepatocytes and mouse 3T3 fibroblasts in the novel integrated discrete multiple organ co-culture (IdMOC) experimental system: results with model toxicants aflatoxin B1, cyclophosphamide and tamoxifen. Li AP, Uzgare A, and LaForge YS Chem. Biol. Interact. 199(1), 1-8, (2012)
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