L6250 Sigma

Lithocholic acid

≥97% (titration)

Synonym: 3α-Hydroxy-5β-cholan-24-oic acid, 3α-Hydroxy-5β-cholanic acid, 5β-Cholan-24-oic acid-3α-ol

Properties

Related Categories Bile acids and Derivatives, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, L,
assay   ≥97% (titration)
mp   183-188 °C(lit.)
Gene Information   human ... POLA1(5422), TOP2A(7153)
rat ... Polb(29240)

Description

Application

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Lithocholic acid has been used in a study to assess cholestasis and its action on several organs and tissues in rats. 1 It has also been used in a study to investigate the regulation of hepatic phospholipid and bile acid homeostasis through SMAD3 activation by TGFβ. 2

Biochem/physiol Actions

Bile Acid

General description

Lithocholic acid is an oligo(ethylene glycol) derivative of bile acid. 3

Packaging

10, 25 g in poly bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. L6250.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Price and Availability

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Cholic acid

from ox or sheep bile, ≥98%

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≥99% (TLC and titration)

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