• USA Home
  • L6516 - Lymphotactin from mouse

L6516 Sigma

Lymphotactin from mouse

>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, cell culture tested

Synonym: Lptn



Related Categories Cell Biology, Cell Signaling and Neuroscience, Chemokines, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones,
recombinant   expressed in E. coli
assay   >97% (SDS-PAGE)
form   lyophilized powder
impurities   endotoxin, tested
suitability   cell culture tested
storage temp.   −20°C
Gene Information   mouse ... Xcl1(16963)


Analysis Note

The biological activity is measured by its ability to chemoattract 3 week IL-2 cultured human lymphocytes and mouse BaF/3 cells transfected with hXCR1.

Physical form

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 1.25 mg bovine serum albumin.

Biochem/physiol Actions

Lymphotactin (Lptn), a member of the C or γ subfamily of chemokines, is similar to members of the CC and CXC chemokine families, but lacks two of the four cysteine residues. Recombinant mouse lymphotactin has chemotactic activity for lymphocytes, NK cells, and mouse splenocytes, but not for monocytes or neutrophils.

Lymphotactin (XCL1) participates in the formation of lung granuloma. In humans, HIV (human immunodeficiency virus)-1 protein, Tat, upregulates XCL1 expression. Lymphotactin might be involved in the CNS (central nervous system) infiltration of T lymphocytes, leading to HIV-1-mediated neurological diseases.

General description

Lymphotactin (XCL1) is generated by activated CD8+ T cells, Th1 (T helper)-polarized CD4+ T cells and NK (natural killer) cells. XCR1 (XC chemokine receptor 1) is a lymphotactin receptor.

Price and Availability

All labs need water
Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?