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L6785 Sigma

Lactacystin

≥90% (HPLC)

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Description

Biochem/physiol Actions

Cell-permeable and irreversible proteasome inhibitor (Ki = 4 nM). Inhibits NF-κB activation (IC50 = 10 μM). Induces neurite outgrowth in neuro 2A mouse neuroblastoma cells.

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Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Discover Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

Exposure to harsh conditions, cellular damage, and other factors can cause stress on cells. Stress attributed directly and indirectly to oxygen is referred to as oxidative stress, which is imposed on...
Keywords: Antimicrobials, Bioactive small molecules, Cancer, Diseases, Neurodegenerative Diseases, Oxidations

Peer-Reviewed Papers
15

References

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