|Related Categories||Agonists, Alkaloids, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography,|
|drug control||USDEA Schedule I; Home Office Schedule 1; stupéfiant; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada|
human ... DRD2(1813), HTR1A(3350), HTR2A(3356), HTR2C(3358), HTR6(3362)|
rat ... Htr1a(24473), Htr2a(29595), Htr2c(25187), Htr7(65032)
Potent hallucinogen; non-selective serotonin receptor agonist.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P260-P264-P280-P284-P302 + P350-P310|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T+|
|Risk Statements (Europe)||26/27/28-40|
|Safety Statements (Europe)||22-28-36-45|
|RIDADR||UN 2811 6.1 / PGII|
Serotonin (5-hydroxytryptamine, 5-HT) is widely distributed throughout the mammalian body, being synthesized from L-tryptophan in enterochromaffin cells of the gastro-intestinal tract as well as in s...
Keywords: Active transport, Atomic absorption spectroscopy, Cancer, Clinical, Gene expression, Ligands, Neurotransmitters, Obesity, Polymorphisms, Schizophrenia, Transduction
Recreational use of D-lysergamide from the seeds of Argyreia nervosa, Ipomoea tricolor, Ipomoea violacea, and Ipomoea purpurea in Poland. Juszczak GR and Swiergiel AH J. Psychoactive Drugs 45(1), 79-93, (2013)
Illicit use of LSD or psilocybin, but not MDMA or nonpsychedelic drugs, is associated with mystical experiences in a dose-dependent manner. Lyvers M and Meester M J. Psychoactive Drugs 44(5), 410-7, (2012)
Dispersive liquid-liquid microextraction prior to field-amplified sample injection for the sensitive analysis of 3,4-methylenedioxymethamphetamine, phencyclidine and lysergic acid diethylamide by capillary electrophoresis in human urine. Airado-Rodríguez D, Cruces-Blanco C, and García-Campaña AM J. Chromatogr. A 1267, 189-97, (2012)
Phospholipase C mediates (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-, but not lysergic acid diethylamide (LSD)-elicited head bobs in rabbit medial prefrontal cortex. Schindler EA, Harvey JA, and Aloyo VJ Brain Res. 1491, 98-108, (2013)
Ligand-dependent conformations and dynamics of the serotonin 5-HT(2A) receptor determine its activation and membrane-driven oligomerization properties. Shan J, Khelashvili G, Mondal S, et al. PLoS Comput. Biol. 8(4), e1002473, (2012)
Impact of high-pressure processing on vitamin E (α-, γ-, and δ-tocopherol), vitamin D (cholecalciferol and ergocalciferol), and fatty acid profiles in liquid foods. Barba FJ, Esteve MJ, and Frigola A J. Agric. Food Chem. 60(14), 3763-8, (2012)
Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Schindler EA, Dave KD, Smolock EM, et al. Pharmacol. Biochem. Behav. 101(1), 69-76, (2012)
Inter-relationship between different platelet measures of 5-HT and their relationship to aggression in human subjects. Marseille R, Lee R, and Coccaro EF Prog. Neuropsychopharmacol. Biol. Psychiatry 36(2), 277-81, (2012)
Agonist-directed signaling of serotonin 5-HT2C receptors: differences between serotonin and lysergic acid diethylamide (LSD). Backstrom, J.R. Neuropsychopharmacology 21, 77, (1999)
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