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L7022 Sigma

Sodium L-lactate

~98%

Synonym: (S)-2-Hydroxypropionic acid sodium salt, L-Lactic acid sodium salt, Sarcolactic acid sodium salt

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Description

Biochem/physiol Actions

L-lactate is produced from pyruvate by the enzyme Lacate Dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells.

Packaging

5, 10, 50 g in glass bottle

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Aerobic Glycolysis and the Warburg Effect

The Warburg effect is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer ce...
Keywords: Aerobic, Biofiles, Cancer, Cell proliferation, Clinical, Glycolysis, PAGE, Phosphorylations, Support, Transcription

Glutamine Metabolism is Dysregulated in Many Cancer Cells

Proliferatively active cells require both a source of carbon and of nitrogen for the synthesis of macromolecules. Although a large proportion of tumor cells utilize aerobic glycolysis and shunt metab...
Keywords: Aerobic, Biofiles, Cancer, Citric Acid Cycle, Gene expression, Glycolysis, Metabolism, Metabolites, PAGE, Phosphorylations, Support, Transcription

Peer-Reviewed Papers
15

References

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