Luteolin

Papers

Radioprotective effect of antioxidative flavonoids in gamma-ray irradiated mice. Shimoi, L., et al. Carcinogenesis 15, 2669, (1994)

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Flavonoid antioxidants: rate constants for reactions with oxygen radicals. Bors, W, et al. Meth. Enzymol. 234, 420, (1994)

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Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase. Alex N Bullock et al J. Med. Chem. 48, 7604-14, (2005)

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Synthesis and biological evaluation of 1,3-diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases and lipoxygenases. P N Praveen Rao et al Bioorg. Med. Chem. Lett. 15, 4842-5, (2005)

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The transgenic Arabidopsis plant system, pER8-GFP, as a powerful tool in searching for natural product estrogen-agonists/antagonists. Fang-Rong Chang et al J. Nat. Prod. 68, 971-3, (2005)

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Expanding the ChemGPS chemical space with natural products. Josefin Larsson et al J. Nat. Prod. 68, 985-91, (2005)

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Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases. P N Praveen Rao et al J. Med. Chem. 49, 1668-83, (2006)

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Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. Deniz Tasdemir et al J. Med. Chem. 49, 3345-53, (2006)

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Fatty acid synthase inhibitory activity of acylphloroglucinols isolated from Dryopteris crassirhizoma. MinKyun Na et al Bioorg. Med. Chem. Lett. 16, 4738-42, (2006)

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A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets. Bernadette M McArdle et al J. Nat. Prod. 69, 14-7, (2006)

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3-Hydroxychromones as cyclin-dependent kinase inhibitors: synthesis and biological evaluation. Jinho Lee et al Bioorg. Med. Chem. Lett. 17, 1284-7, (2007)

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New antifungal flavonoid glycoside from Vitex negundo. B Sathiamoorthy et al Bioorg. Med. Chem. Lett. 17, 239-42, (2007)

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Rotenoids and flavonoids with anti-invasion of HT1080, anti-proliferation of U937, and differentiation-inducing activity in HL-60 from Erycibe expansa. Hisashi Matsuda et al Bioorg. Med. Chem. 15, 1539-46, (2007)

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Improved quantitative structure-activity relationship models to predict antioxidant activity of flavonoids in chemical, enzymatic, and cellular systems. Andrei I Khlebnikov et al Bioorg. Med. Chem. 15, 1749-70, (2007)

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2-Styrylchromones: novel strong scavengers of reactive oxygen and nitrogen species. Ana Gomes et al Bioorg. Med. Chem. 15, 6027-36, (2007)

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Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase. Sheldon Holder et al Bioorg. Med. Chem. 15, 6463-73, (2007)

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Cells lacking DNA topoisomerase II beta are resistant to genistein. Miguel López-Lazaro et al J. Nat. Prod. 70, 763-7, (2007)

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Chemical genetics reveals a complex functional ground state of neural stem cells Diamandis, P., et. al. Nat. Chem. Biol. 3(5), 268-273, (2007)

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Flavonoids for controlling starch digestion: structural requirements for inhibiting human alpha-amylase. Elena Lo Piparo et al J. Med. Chem. 51, 3555-61, (2008)

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Structure-activity relationship of human GLO I inhibitory natural flavonoids and their growth inhibitory effects. Ryoko Takasawa et al Bioorg. Med. Chem. 16, 3969-75, (2008)

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Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities. Ai-Lin Liu et al Bioorg. Med. Chem. 16, 7141-7, (2008)

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Tyrosine derivatives isolated from Streptomyces sp. IFM 10937 in a screening program for TRAIL-resistance-overcoming activity. Firoj Ahmed et al J. Nat. Prod. 71, 1963-6, (2008)

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Steroids and flavonoids from Physalis alkekengi var. franchetii and their inhibitory effects on nitric oxide production. Li Qiu et al J. Nat. Prod. 71, 642-6, (2008)

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Erigeroflavanone, a flavanone derivative from the flowers of Erigeron annuus with protein glycation and aldose reductase inhibitory activity. Nam Hee Yoo et al J. Nat. Prod. 71, 713-5, (2008)

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Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay. Yosuke Nishizaki et al Bioorg. Med. Chem. Lett. 19, 4706-10, (2009)

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Structural characteristics of flavanones and flavones from Cudrania tricuspidata for neuraminidase inhibition. Young Bae Ryu et al Bioorg. Med. Chem. Lett. 19, 4912-5, (2009)

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Glucose-containing flavones--their synthesis and antioxidant and neuroprotective activities. Seung Hwan Kim et al Bioorg. Med. Chem. Lett. 19, 6009-13, (2009)

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Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities. Hyung Jae Jeong et al Bioorg. Med. Chem. 17, 6816-23, (2009)

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Synthesis and biological evaluation of novel luteolin derivatives as antibacterial agents. Peng-Cheng Lv et al Eur. J. Med. Chem. 44, 908-14, (2009)

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Chemical constituents from the aerial parts of Artemisia minor. Zhi-Zhou He et al J. Nat. Prod. 72, 1198-201, (2009)

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Cardenolide glycosides of Thevetia peruviana and triterpenoid saponins of Sapindus emarginatus as TRAIL resistance-overcoming compounds. Takashi Miyagawa et al J. Nat. Prod. 72, 1507-11, (2009)

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Triterpenoids and flavonoids from celery (Apium graveolens). Kailan Zhou et al J. Nat. Prod. 72, 1563-7, (2009)

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Inhibition studies of bovine xanthine oxidase by luteolin, silibinin, quercetin, and curcumin. James M Pauff et al J. Nat. Prod. 72, 725-31, (2009)

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Small-molecule inhibitors of NADPH oxidase 4. Gábor Borbély et al J. Med. Chem. 53, 6758-62, (2010)

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The synthesis and angiotensin converting enzyme (ACE) inhibitory activity of chalcones and their pyrazole derivatives. Marco Bonesi et al Bioorg. Med. Chem. Lett. 20, 1990-3, (2010)

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New inhibitors for expression of IgE receptor on human mast cell. Satoru Tamura et al Bioorg. Med. Chem. Lett. 20, 2299-302, (2010)

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Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosides. Ping Wang et al Bioorg. Med. Chem. Lett. 20, 2790-6, (2010)

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Integrated ligand and structure based studies of flavonoids as fatty acid biosynthesis inhibitors of Plasmodium falciparum. Amit K Gupta et al Bioorg. Med. Chem. Lett. 20, 4779-81, (2010)

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Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. Jingjing Yao et al Bioorg. Med. Chem. Lett. 20, 56-9, (2010)

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Flavonoids from Dracocephalum tanguticum and their cardioprotective effects against doxorubicin-induced toxicity in H9c2 cells. Shu-Qi Wang et al Bioorg. Med. Chem. Lett. 20, 6411-5, (2010)

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Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea. Chia-Lin Lee et al Bioorg. Med. Chem. Lett. 20, 7354-7, (2010)

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A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors. Franco Chimenti et al Bioorg. Med. Chem. 18, 1273-9, (2010)

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Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase. Shingo Arioka et al Bioorg. Med. Chem. 18, 1633-40, (2010)

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Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells. Souichi Nakashima et al Bioorg. Med. Chem. 18, 2337-45, (2010)

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Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids. Dragan Ami? et al Bioorg. Med. Chem. 18, 28-35, (2010)

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Synthesis of a novel series of diphenolic chromone derivatives as inhibitors of NO production in LPS-activated RAW264.7 macrophages. Guo-Biao Liu et al Bioorg. Med. Chem. 18, 2864-71, (2010)

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Selective inhibition of methoxyflavonoids on human CYP1B1 activity. Hitomi Takemura et al Bioorg. Med. Chem. 18, 6310-5, (2010)

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Discovery and synthesis of novel luteolin derivatives as DAT agonists. Jiange Zhang et al Bioorg. Med. Chem. 18, 7842-8, (2010)

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Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme. Isabelle Kuhn et al Bioorg. Med. Chem. 18, 7900-10, (2010)

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Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition. Young Bae Ryu et al Bioorg. Med. Chem. 18, 7940-7, (2010)

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QSAR study of flavonoids and biflavonoids as influenza H1N1 virus neuraminidase inhibitors. Andrew G Mercader et al Eur. J. Med. Chem. 45, 1724-30, (2010)

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Structural aspects of flavonoids as inhibitors of human butyrylcholinesterase. Maja Katalini? et al Eur. J. Med. Chem. 45, 186-92, (2010)

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Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98. Eduardo Borges de Melo et al Eur. J. Med. Chem. 45, 4562-9, (2010)

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An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. Yunbao Liu et al J. Nat. Prod. 73, 1193-5, (2010)

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Phloroglucinol glycosides from the fresh fruits of Eucalyptus maideni. Li-Wen Tian et al J. Nat. Prod. 73, 160-3, (2010)

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Flavonoids as inhibitors of human CD38 E. Kellenberger, et al., Bioorg. Med. Chem. Lett. 21, 3939-3942, (2011)

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Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells. Hisashi Matsuda et al Bioorg. Med. Chem. 19, 2835-41, (2011)

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Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids. Vasilis P Androutsopoulos et al Bioorg. Med. Chem. 19, 2842-9, (2011)

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Synthesis and evaluation of novel 2-butyl-4-chloro-1-methylimidazole embedded chalcones and pyrazoles as angiotensin converting enzyme (ACE) inhibitors. Srinivas Kantevari et al Bioorg. Med. Chem. 19, 4772-81, (2011)

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Protective effects of luteolin against apoptotic liver damage induced by D-galactosamine/lipopolysaccharide in mice. Woo-Cheol Lee et al J. Nat. Prod. 74, 1916-21, (2011)

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Cycloartane triterpenes isolated from Combretum quadrangulare in a screening program for death-receptor expression enhancing activity. Kazufumi Toume et al J. Nat. Prod. 74, 249-55, (2011)

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Flavonoids from eight tropical plant species that inhibit the multidrug resistance transporter ABCG2. Muhammad Ali Versiani et al J. Nat. Prod. 74, 262-6, (2011)

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Merck 14,5614