Synonym: Diacylglycerol acylhydrolase, Diacylglycerol lipase, Lipoprotein Lipase from Pseudomonas sp.
CAS Number 9004-02-8
EC Number 232-669-1
MDL number MFCD00131523
Popular Documents: Specification Sheet (PDF)
| Related Categories | 3.1.x.x Acting on esters, 3.x.x.x Hydrolases, Biochemicals and Reagents, Enzyme Class Index, Enzymes, Inhibitors, and Substrates, |
| form | lyophilized powder |
| storage temp. | −20°C |
Lipoprotein lipase hydrolyzes triglycerides in plasma lipoproteins causing release of fatty acids for metabolic purposes in muscles and adipose tissue. 4
One unit will release 1.0 nmole of p-nitrophenol per min at pH 7.2 at 37 °C using p-nitrophenyl butyrate as substrate.
Lipoprotein lipase has been used in a study to assess the role of lipogenic enzymes in colorectal cancer. 1 It has also been used in a study to investigate lipasemic activity of low molecular weight heparin in rats. 2
Due to its lipolytic activity, lipoprotein lipase was shown to effectively block the spread of hepatitis C virus into healthy cells. 3
Lipoprotein lipase belongs to the family of triglyceride lipases. It hydrolyses triglycerides in triglyceride-rich ApoB-containing lipoproteins.
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